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SINEUPs broadly promote translation of mammalian m RNA they pair with, since the antisense fraction can be synthesized against 5’ untranslated regions (5’ UTRs) of any m RNAs.

I married my wife several months ago after dating three years.

”- a collection of the most ridiculous, obscene,and sometimes just plain sad search terms people have used to find my blog. Because, like, not to be a Debbie Downer or anything, but it sounds kind of dangerous. And everyone’s up-to-date emergency contact information. ) and decided that life really was worth living after all. That’s why I thought I would help by identifying a few suggestions: …..

(If you missed the first installment, you can find it here.) Below are just a few of my favorites- along with some color commentary. also, apparently marshmallow peep dioramas are a thing: ….

She is very contrite and swears she will calm down the flirtation. Or should I run the hell away before it's too late? I'm wary of accepting your characterization of her behavior at face value, STH, as your overreaction to the kiss leads me to believe that you might not be rational about your wife's behavior generally.

Anyway, today, I’m going to lighten the mood a little by resurrecting a feature I like to call: “You Googled What?? Think I was curious what ever happened to Mark Curry (aka Mr. Apparently, he is now on the Nick-at-Nite family show See Dad Run with Scott Baio (!! He also got burned pretty badly a few years back after a can of aerosol spray exploded in his house, and he contemplated suicide for a while, until he talked to Sinbad (!!! If you answered yes to 87% or more of these questions, then I’m sorry to tell you that yes, you are a card-carrying member of the Forever Single Club. In the words of the King Of Pop: Finding the “best diorama ever” is an incredibly noble pursuit. My heart breaks for the poor, insecure girl who searched this. Or from a pile of other pieces of yarn, some of which new, some of which “leftover”?

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Despite recent efforts in discovering novel long non-coding RNAs (lnc RNAs) and unveiling their functions in a wide range of biological processes their applications as biotechnological or therapeutic tools are still at their infancy.We have recently shown that AS Uchl1, a natural lnc RNA antisense to the Parkinson's disease-associated gene Ubiquitin carboxyl-terminal esterase L1 (Uchl1), is able to increase Uch L1 protein synthesis at post-transcriptional level.Its activity requires two RNA elements: an embedded inverted SINEB2 sequence to increase translation and the overlapping region to target its sense m RNA.While she acknowledges that a line was crossed (which is why she didn't tell me when it happened), she says it was just a very intense but regrettable "friendship moment" and nothing more. I'm grappling with three issues: (1) Did she cheat?Although we've never talked about the rules concerning kissing gay friends, we both know she crossed a line (there was tongue).Things are generally excellent, except for one problem: When my wife gets drunk, she gets crazy flirtatious.